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Maureen Barr
Maureen Barr
Professor
...
(848) 445-1639
(732) 445-1147
LSB-324
Life Sciences Bldg. Rutgers University 145 Bevier Road Piscataway, NJ, 08854

Biography

1990  B.A. Rutgers University, New Brunswick, NJ, Biology

1995  Ph.D. Columbia University, New York, NY, Genetics and Development

1995-2000 Postdoctoral Fellow, California Institute of Technology/HHMI

2000-2007 Faculty (tenured), University of Wisconsin-Madison

2007-2012 Associate Professor, Rutgers Genetics

2012  Full professor, Rutgers Genetics

Research

Modeling human genetic diseases in C. elegans. The Barr laboratory is interested two seemingly unrelated questions in biology: the generation of sexual identity and the molecular basis of human genetic diseases of cilia. In particular, we study male mating behavior and ciliary specialization in the nematode Caenorhabditis elegans. My laboratory currently uses several approaches to study animal physiology and behavior, including dissection of neural circuits, the identification of genes required for nervous system development and function, and in vivo imaging of neuronal protein trafficking. Chemical genetics and electrophysiology are being explored.

Publications

SELECT PUBLICATIONS

Silva, M., Morsci, N., Nguyen, K.C.Q., Rizvi, A., Rongo, C., Hall, D.H., and Barr, M.M. (2017) “Cell-specific alpha-tubulin isotype regulates ciliary microtubule ultrastructure, intraflagellar transport, and extracellular vesicle biology.” Current Biology 27: 968-980.

Wang, J. & Barr, M.M. (2016) Ciliary extracellular vesicles: Txt Msg Organelles. Cell Mol Neurobiol. 36(3):449-57.

Wang, J., Kaletski, R., Silva, M., Williams, A., Haas, L.A., Androwski, R.J., Landis, J.N., Patrick, C., Rashid, A., Santiago-Martinez, D., Gravato-Noble, M., Hodgkin, J., Hall, D.H., Murphy, C.T. and Barr, M.M. (2015). “Cell Specific Transcriptional Profiling of Ciliated Extracellular Vesicle Releasing Neurons Reveals Regulators of Behavior and Extracellular Vesicle Biogenesis.” Current Biology 25: 1-7.

Warburton-Pitt, S., Silva, M., Nguyen, K.C., Hall, D.H. and Barr, M.M. (2014) The nphp-2 and arl-13 Genetic Modules Interact to Regulate Ciliogenesis and Ciliary Microtubule Patterning in C. elegans. PLOS Genetics. 10(12): e1004866. doi: 10.1371/journal.pgen.1004866

Wang, J., Silva, M., Haas, L.A., Morsci, N.S., Nguyen, K.C., Hall, D.H., and Barr, M.M. (2014) C. elegans ciliated neurons release extracellular vesicles that function in animal communication. Current Biology 24: 519-25.

 

 

Lab Page

barrlab.rutgers.edu/index.html
Maureen Barr

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