Michael Sheldon Profile Page
Michael Sheldon
Associate Research Professor
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(848) 445-7096
(732) 445-1149
Nelson C241
604 Allison Road, Piscataway, NJ 08854-8082

Research

Stem Cell Biology and Mammalian Brain Development

Publications

  • Li, R., Paul, A., Ko, K.W., Sheldon, M., Rich, B.E., Terashima, T., Dieker, C., Cormier, S., Li, L., Nour, E.A., Chan, L., and Oka, K. (2011). Interleukin-7 induces recruitment of monocytes/macrophages to endothelium. Eur Heart J.doi:10.1093/eurheartj/ehr245. http://eurheartj.oxfordjournals.org/content/early/2011/07/30/eurheartj.ehr245.short?rss=1
  • Sanders S.J., et al., (2011). Multiple recurrent de novo CNVs, including duplications of the 7q11.23 Williams syndrome region, are strongly associated with autism. Neuron 70, 863-885. http://www.sciencedirect.com/science/article/pii/S0896627311003746
  • Lu, X-Y., Lu, Y., Zhao, Y.J., Jaeweon, K., Kang, J., Xiao-Nan, L., Ge, G., Meyer, R., Perlaky, L., Hicks, J., Chintagumpala, M., Cai, W-W., Ladanyi, M., Gorlick, R., Lau, C.C., Pati, D., Sheldon, M., and Rao, P.H.. (2008). Cell cycle regulator gene CDC5L, a potential target for 6p12-p21 amplicon in osteosarcoma. Mol Cancer Res 6, 937-946. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693718/
  • Ljungberg, M.C., Bhattacharjee, M.B., Lu, Y., Armstrong, D.L., Yoshor, D., Swann, J.W., Sheldon, M., and D'Arcangelo, G. (2006). Activation of mammalian target of rapamycin in cytomegalic neurons of human cortical dysplasia. Ann Neurol 60, 420-429. http://onlinelibrary.wiley.com/doi/10.1002/ana.20949/abstract;jsessionid=944870653FDAB7F5FFF23F1EBBC8B9BC.d03t04
  • Niu, S., Renfro, A., Quattrocchi, C.C., Sheldon, M., and D'Arcangelo, G. (2004). Reelin promotes hippocampal dendrite development through the VLDLR/ApoER2-Dab1 pathway. Neuron 41, 71-84. http://www.sciencedirect.com/science/article/pii/S0896627303008195
  • Deguchi, K., Inoue, K., Avila, W.E., Lopez-Terrada, D., Antalffy, B.A., Quattrocchi, C.C., Sheldon, M., Mikoshiba, K., D'Arcangelo, G., and Armstrong, D.L. (2003). Reelin and disabled-1 expression in developing and mature human cortical neurons. J Neuropathol Exp Neurol 62, 676-684. PDF in Appendix
  • Assadi, A.H., Zhang, G., Beffert, U., McNeil, R.S., Renfro, A.L., Niu, S., Quattrocchi, C.C., Antalffy, B.A., Sheldon, M., Armstrong, D.D., Wynshaw-Boris A., Herz J., D'Arcangelo G., and Clark G.D.. (2003). Interaction of reelin signaling and Lis1 in brain development. Nat Genet 35, 270-276. http://www.nature.com/ng/journal/v35/n3/full/ng1257.html
  • Lu, X.Y., Harris, C.P., Cooley, L., Margolin, J., Steuber, P.C., Sheldon, M., Rao, P.H., and Lau, C.C. (2002). The utility of spectral karyotyping in the cytogenetic analysis of newly diagnosed pediatric acute lymphoblastic leukemia. Leukemia 16, 2222-2227. http://www.nature.com/leu/journal/v16/n11/full/2402662a.html
  • D'Arcangelo, G., Homayouni, R., Keshvara, L., Rice, D.S., Sheldon, M., and Curran, T. (1999). Reelin is a ligand for lipoprotein receptors. Neuron 24, 471-479. http://www.sciencedirect.com/science/article/pii/S0896627300808600
  • Homayouni, R., Rice, D.S., Sheldon, M., and Curran, T. (1999). Disabled-1 binds to the cytoplasmic domain of amyloid precursor-like protein 1. J Neurosci 19, 7507-7515. http://www.jneurosci.org/content/19/17/7507.long
  • Alvarez-Dolado, M., Ruiz, M., Del Rio, J.A., Alcantara, S., Burgaya, F., Sheldon, M., Nakajima, K., Bernal, J., Howell, B.W., Curran, T., Soriano E., and Muñoz A.(1999). Thyroid hormone regulates reelin and dab1 expression during brain development. J Neurosci 19, 6979-6993. http://www.jneurosci.org/content/19/16/6979.long
  • Reinberg, D.,et al., (1998). The RNA polymerase II general transcription factors: past, present, and future. Cold Spring Harb Symp Quant Biol 63, 83-103. PDF in Appendix
  • Rice, D.S., Sheldon, M., D'Arcangelo, G., Nakajima, K., Goldowitz, D., and Curran, T. (1998). Disabled-1 acts downstream of Reelin in a signaling pathway that controls laminar organization in the mammalian brain. Development 125, 3719-3729. http://dev.biologists.org/content/125/18/3719.long
  • Goldowitz, D., Cushing, R.C., Laywell, E., D'Arcangelo, G., Sheldon, M., Sweet, H.O., Davisson, M., Steindler, D., and Curran, T. (1997). Cerebellar disorganization characteristic of reeler in scrambler mutant mice despite presence of reelin. J Neurosci 17, 8767-8777. http://www.jneurosci.org/content/17/22/8767.long
  • Sheldon, M., Rice, D.S., D'Arcangelo, G., Yoneshima, H., Nakajima, K., Mikoshiba, K., Howell, B.W., Cooper, J.A., Goldowitz, D., and Curran, T. (1997). Scrambler and yotari disrupt the disabled gene and produce a reeler-like phenotype in mice. Nature 389, 730-733. http://www.nature.com/nature/journal/v389/n6652/full/389730a0.html
  • Maldonado, E., Shiekhattar, R., Sheldon, M., Cho, H., Drapkin, R., Rickert, P., Lees, E., Anderson, C.W., Linn, S., and Reinberg, D. (1996). A human RNA polymerase II complex associated with SRB and DNA-repair proteins. Nature 381, 86-89. http://www.nature.com/nature/journal/v381/n6577/abs/381086a0.html PDF in Appendix
  • Sun, X., Ma, D., Sheldon, M., Yeung, K., and Reinberg, D. (1994). Reconstitution of human TFIIA activity from recombinant polypeptides: a role in TFIID-mediated transcription. Genes Dev 8, 2336-2348 http://genesdev.cshlp.org/content/8/19/2336.long
  • Sheldon, M., Ratnasabapathy, R., and Hernandez, N. (1993). Characterization of the inducer of short transcripts, a human immunodeficiency virus type 1 transcriptional element that activates the synthesis of short RNAs. Mol Cell Biol 13, 1251-1263. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC359010/
  • Hernandez, N., Lobo, S., Lister, J., Ifill, S., Ratnasabapathy, R., Sheldon, M., and Johal, L. (1990). Transcription of the human U2 and U6 RNA genes. Mol Biol Rep 14, 167. http://www.springerlink.com/content/j676x32313104382/
  • Ratnasabapathy, R., Sheldon, M., Johal, L., and Hernandez, N. (1990). The HIV-1 long terminal repeat contains an unusual element that induces the synthesis of short RNAs from various mRNA and snRNA promoters. Genes Dev 4, 2061-2074. http://genesdev.cshlp.org/content/4/12a/2061.long
  • Hassold, T., Jacobs, P.A., Leppert, M., and Sheldon, M. (1987). Cytogenetic and molecular studies of trisomy 13. J Med Genet 24, 725-732. http://jmg.bmj.com/content/24/12/725.long

Lab Page

NIMH Stem Cell Resource