Past Events

“Mouse genetics provide insight into molecular mechanisms of mouse and human fertilization”

Monday, February 29, 2016, 12:00pm - 01:00pm

Laboratory of Cellular and Developmental Biology
National Institutes of Health, NIDDK
Bethesda, MD

 

Avella MA resize

 

Abstract: Fertilization requires sperm binding to the extracellular zona pellucida (ZP) that surrounds ovulated eggs. Using mouse genetics, the N terminus of ZP2 was defined as the domain essential and sufficient for gamete recognition. These findings have compelling implications in reproductive medicine and serve as a proxy for the identification of the sperm membrane receptor for the zona pellucida.

Location 
Life Sciences Building, 145 Bevier Rd, Busch Campus, Auditorium
Contact 
Mary Carmona/ email: / phone: 848-445-1638