Past Events
Finding Gene-Gene Interactions in Complex Disease Susceptibility: asthma as an example |
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Monday, May 02, 2016, 12:00pm - 01:00pm |
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Andrew Dewan, PhD. Department of Chronic Disease Epidemiology Yale University School of Public Health
Abstract: Gene-gene interaction, or epistasis, is the phenomenon where the phenotypic effect of a genetic variant at one locus depends on variants at another locus. Epistasis is thought to be biologically pervasive and to contribute to the genetic etiology of complex human disease. However, the identification of gene-gene interactions is made particularly challenging due to their high-dimensional nature. I will summarize an evaluation of the epistasis for asthma as well as several studies to identify novel gene-gene interactions using available datasets.
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Location | |||||||||
Life Sciences Bldg., Auditorium, 145 Bevier Rd, Piscataway, Busch Campus | |||||||||
Contact | |||||||||
Host: Dr. Derek Gordon phone: 848-445-3386/ email: | |||||||||
Andrew Dewan, PhD./ Department of Chronic Disease Epidemiology/ Yale University School of Public Health/ New Haven, Ct |
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