Related to Alzheimer’s disease

1.   Finelli, A., Kelkar, A., Song, H-J., Yang, H. and Konsolaki, M. (2004).  Alzheimer's Ab42 age-related toxicity can be suppressed by the metalloprotease neprilysin in Drosophila melanogaster neurons.  Mol. Cell. Neurosci. 26, 365-75. 

2.   Iijima, K., Liu, H-P., Chiang, A-S., Hearn, S.A., Konsolaki, M. and Zhong, Y. (2004).  Dissecting the pathological effects of human A40 and A42 in Drosophila: A potential model for Alzheimer's disease. Proc. Natl. Acad. Sci. USA 101, 6623-6628.

3.   Cao, W., Song, H-J., Gangi, T., Kelkar, A., Antani, I., Garza, D., and Konsolaki, M. (2008). Identification of novel genes that modify phenotypes induced by Alzheimer's beta amyloid overexpression in Drosophila. Genetics 178(3):1457-71. PMCID: PMC2278065

4.   Tan, L., Schedl, P., Song, H-J., Garza, D. and Konsolaki, M. (2008).  The Tollà NFkB signaling pathway mediates the neuropathological effects of the human Alzheimer’s Ab42 polypeptide in Drosophila. PLoS ONE  3(12):e3966. PMCID: PMC2597734

5.  van de Hoef, D., Hughes, J., Livne-Bar, I., Garza, D., Konsolaki, M. and Boulianne, G.L. (2009). Identifying Genes that Interact with Drosophila Presenilin and Amyloid Precursor Protein.  Genesis 47(4):246-60

6.  Sanokawa-Akakura, R., Cao W., Allan, K., Patel, K., Ganesh, A., Heiman, G., Burke, R., Kemp, F., Bodgen, J., Camakaris, J., Birge, RB., and Konsolaki, M. (2010). Regulation of Alzheimer’s amyloid beta toxicity by the high molecular weight immunophilin FKbp52 and copper homeostasis. PLoS ONE 5(1): e8626. PMCID: PMC2801609

7.   Cao W, Konsolaki M. (2011) FKBP immunophilins and Alzheimer's disease: A chaperoned affair.  J Biosci.

36(3):493-8.  PMID: 21799260


Additional selected publications

1.    Konsolaki, M., Komitopoulou, K., Tolias, P.P., King, D.L., Swimmer, C. and Kafatos, F.C. (1990).  The chorion genes of the medfly, Ceratitis capitata: I. Structural and regulatory conservation of the s36  gene relative to two Drosophila  species.  Nucl. Acids Res. 18,  1731-1737.

2.    Tolias, P.P., Konsolaki, M., Komitopoulou, K. and Kafatos, F.C. (1990).  The chorion genes of the medfly, Ceratitis capitata:  II. Characterization of three novelcDNA clones obtained by differential screening of an ovarian library.  Dev. Biol. 140, 105-112.

3.    Zacharopoulou, A., Frisardi, M., Savakis, C., Robinson, A., Tolias, P. P., Konsolaki, M., Komitopoulou, K. and Kafatos, F. C. (1991).  The genome of the Mediterranean fruitfly Ceratitis capitata: Localization of molecular markers by in situ  hybridization to salivary gland poletene chromosomes. Chromosoma 101, 448-455.

4.    Aggeli, A., Hamodrakas, S.J., Komitopoulou, K. and Konsolaki, M. (1991)  Tandemly repeating peptide motifs and their secondary structure in  Ceratitis capitata  eggshell proteins Ccs36 and Ccs38. Int. J. Biol. Macromol. 13, 307-316.

5.    Konsolaki, M., Sanicola, M., Kozlova, T., Liu, V., Arca, B., Savakis, C., Gelbart, W.  and Kafatos, F.C. (1992).  FLP- mediated intermolecular recombination in the cytoplasm of Drosophila  embryos.  The New Biologist  4, 551-557.

6.    Tolias, P. P., Konsolaki, M., Halfon, M. S., Stroumbakis, N. and Kafatos, F. C. (1993) Elements controlling follicular expression of the s36 chorion gene during Drosophila oogenesis.  Molecularand Cellular Biology 13, 5898-5906.

7.    Vlachou, D., Konsolaki, M., Tolias, P., Kafatos, F. and Komitopoulou, K. (1997).  The autosomal chorion locus of the medfly Ceratitis capitata I. Conserved synteny, amplification and tissue specificity but sequence divergence and altered temporal regulation.  Genetics 147 (4),1829-1842.

8.    Konsolaki, M. and Schupbach, T. (1998) Windbeutel, a gene required for dorso-ventral patterning in Drosophila, encodes a protein that has homologies to vertebrate proteins of the endoplasmic reticulum. Genes and Development  12(1): 120-131.

9.    Sen, J., Goltz, J.S., Konsolaki, M., Schupbach, T. and Stein D. (2000).  Windbeutel is required for function  and correct subcellular localization of the Drosophila patterning protein Pipe. Development 127, 5541-550