Seminars and Events

HYBRID SEMINAR with Eric C. Lai, Ph.D., “Red queen and the lost boys : Roles for RNAi to silence sex chromosome conflict during speciation””

Eric C. Lai, Ph.D.

Developmental Biology Program Sloan-Kettering Institute
New York, NY

Hosted by Andrew Singson | singson@waksman.rutgers.edu

12PM, Monday, May 9, 2022
Zoom Meeting Link:https://rutgers.zoom.us/meeting/register/tJwrc-ihqTIjGNynMGyBXOvSWN74qaao2xJ_
Meeting ID: 986 4197 9928
Passcode: Genetics

“Red queen and the lost boys : Roles for RNAi to silence sex chromosome conflict during speciation”

RNA interference (RNAi) is well-known as a tool for experimental gene silencing, but its endogenous RNA interference (RNAi) is well-known as a tool for experimental gene silencing, but its endogenous utilities are less understood, especially in metazoans. We are uncovering surprising and profound requirements for endo-RNAi substrates to suppress recently-emerged, selfish genes that manipulate Mendeli  n inheritance. Such intragenomic conflicts and theirresolution may drive speciation.

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