• Tara Matise
  • Tara Matise
  • Position: Distinguished Professor-Chair, Department of Genetics
  • Research Focus: Computational Human Genetics, genetics coordinating center
  • Subset Area: Genetics of Human Disease | CNS, Genetics of Human Disease | Reproductive, Computational Genetics | Bioinformatics, Computational Genetics | Statistical Genetics
  • Phone: (848) 445-3125
  • Address: 604 Allison Road, Piscataway, NJ 08854-8082
  • Office: Nelson B410
  • Research:

    Computational Genetics represents my joint interests in human genetics, data science, statistical genetics, and bioinformatics. The goal of my work is to facilitate the identification of human disease genes. 

    Since 2008 I have been co-director, with Dr. Steve Buyske, of the Coordinating Center (CC) for The PAGE Study (PAGE I 2008-2012; PAGE II 2013-2017). This study investigates population-specific variation in genetic disease susceptibility, focusing on non-European populations. You can read a 2013 press announcement here. For this NIH-funded project the Rutgers coordinating center manages the quality control, integration, and dissemination of the large-scale genotype data generated in PAGE, performs genotype imputation and ancestry deconvolution, organizes group discussions and meetings, facilitates collaborations, and oversees the logistics of the PAGE study. Our work is facilitated by collaborators at the USC/Information Sciences Institute and Stanford University. The CC team members bring expertise in population, statistical, and quantitative human genetics, computer science, genome sequencing and bioinformatics. The CC's combined expertise will help advance PAGE II's research on understanding the global relevance of disease-associated alleles across diverse human populations.

    During 2015-2022 I was co-director, with Dr. Steve Buyske, of the Coordinating Center (CC) for the NHGRI Genome Sequencing Program.  The National Human Genome Research Institute (NHGRI) Genome Sequencing Program (GSP) uses genome sequencing to identify genes and genomic variants underlying human inherited disease across its full spectrum, including rare diseases likely to be due to rare variants with strong effects (Mendelian), and common genetically complex diseases that are caused by many variants. Novel methods, tools, and knowledge gained through the GSP will be rapidly shared to enhance the ability of the community to pursue other human inherited diseases. The GSP Coordinating Center provides scientific leadership and expertise for specific cross-program objectives and coordination for administrative, logistical, and outreach activities.

    Google Scholar for Tara Matise: https://scholar.google.com/citations?user=gKTHzuAAAAAJ&hl=en

  • Publications PubMed: